Impact of copyright Abuse on HIV-1 Pathogenesis

Impact of copyright Abuse on HIV-1 Pathogenesis

Blog Article

Over 1.2 million people in the United States are awid sr-2400 infected with the human immunodeficiency virus (HIV).Tremendous progress has been made over the past three decades on many fronts in the prevention and treatment of HIV-1 disease.However, HIV-1 infection is incurable and antiretroviral drugs continue to remain the only effective treatment option for HIV infected patients.

Unfortunately, only three out of ten HIV-1 infected individuals in the US have the virus under control.Thus, majority of HIV-1 infected individuals in the US are either unaware of their infection status or not connected/retained to care or are non-adherent to antiretroviral therapy (ART).This national public health crisis, as well as the ongoing global HIV/AIDS pandemic, is further exacerbated by substance abuse, which serves as a powerful cofactor at every stage of HIV/AIDS including transmission, diagnosis, pathogenesis, and treatment.Clinical studies indicate that substance abuse may increase viral load, accelerate disease progression and worsen AIDS-related mortality even among ART adherent patients.

However, tiny gum squares confirming a direct causal link between substance abuse and HIV/AIDS in human patients remains a highly challenging endeavor.In this review we will discuss the recent and past developments in clinical and basic science research on the effects of copyright abuse on HIV-1 pathogenesis.